Musi wa15 Zvita 2025, National Medical Products Administration yeChina yakabvumidza zviri pamutemo kuburitswa kwemushonga mutsva wekurwisa kenza we zurletrectinib (ICP-723) pamusika. Kubudirira uku kunounza tariro yekurapa isingaenzaniswi kuvarwere pasi rese vane bundu rakasimba rine majini eNTRK fusion.
**Kurapa kwe "Tumor-Agnostic" kweChimurenga: Kubudirira kweSainzi kweZurletrectinib**
Zurletrectinib ndiyo mushonga wekutanga weTRK wechizvarwa chitsva wakaburitswa wega muChina, wakagadzirirwa varwere vane bundu rakasimba remuno kana kuti rakapararira rine majini eNeurotrophic Tyrosine Receptor Kinase (NTRK) fusion. Uyu mushonga we "bundu-agnostic" wekudzivirira kenza une "broad-spectrum" unomiririra shanduko huru mumunda wekurapa kenza—kuchinja kubva pakupatsanurwa kwenzvimbo yechinyakare uye kurapwa kwakavakirwa pamavambo kuenda kukurapa kwakanangana nehunyanzvi zvichibva pakuchinja kwemajini.
**Zviratidzo Zvikuru:**
* Varwere vakaonekwa kuti vane gene reNTRK fusion kuburikidza nekuongororwa kwakasimbiswa zvizere (kunze kwekuchinja kweresistance kunozivikanwa).
* Varwere vakuru nevachiri kuyaruka (vane makore gumi nemaviri zvichikwira) vane bundu rakasimba vasina imwe nzira yekurapa inogutsa kana kuti vane kurapwa kwakamboitwa kwakakundikana.
**Benefit Yepakati:**
Chero bedzi gene reNTRK fusion rikaonekwa kuburikidza nekuongororwa kwemajini, varwere vanogona kubatsirwa zvakanyanya nekurapwa nezurletrectinib, zvisinei nekuti bundu iri rakatangira mumapapu, thyroid, zamu, ura, kana dzimwe nzvimbo.
**Ruzivo Rwakanaka rweKurapa: Kutsanangura Patsva Zvinotarisirwa paKurapwa**
Miedzo yekiriniki ye zurletrectinib yakaitwa muChina yakaratidza ruzivo rwakanaka rwekushanda zvakanaka, zvichipa tariro yakakura yekupona kune varwere vane bundu rakasimba repamusoro:
* **Mhinduro Yese Yekupindura (ORR): 89.1%** — Vanenge 90% yevarwere vakatambura nekuderera kukuru kwebundu.
* **Kudzora Kurwara (DCR): 96.4%** — Kufambira mberi kwechirwere kwakadzorwa zvinobudirira muvarwere vanenge vese.
* **Kurarama Pasina Kufambira Mberi Kwemwedzi 24 (PFS): 77.4%** — Kudzora kufambira mberi kwechirwere kwenguva refu.
* **Chiyero cheKupona Kwese Kwemwedzi 24 (OS): 90.8%** — Nguva yekurarama kwemurwere yakawedzera zvakanyanya.
**Dhipatimendi Repasirose reBeijing South Region Oncology Hospital: Nzira Yenyu Yekurapa Gomarara Rakakosha**
Dhipatimendi reBeijing South Region Oncology Hospital International rakatsunga kupa varwere vepasi rose mukana wekuwana nzira dzekurapa kenza dzemhando yepamusoro. Chikwata chedu chekurapa chepasi rose chakazvipira kupa rutsigiro rwakakwana rwekurapa kune murwere wese wepasi rose.
Mabasa edu akakosha anosanganisira:
1. Kubvunzana nekuongorora kurapwa kwevarwere pasi rose.
2. Kurongeka uye kududzirwa kwekuongororwa kwemajini ekubatanidza NTRK.
3. Kubvunzana nenyanzvi dzemhando dzakasiyana-siyana uye kuronga kurapwa kwakazara.
4. Rutsigiro rwekushandura mitauro yakawanda panyaya dzekurapa uye tsika.
**Bata Dhipatimendi reInternational Hospital Oncology reBeijing South Region**
Tinonzwisisa matambudziko anosangana nevarwere vekune dzimwe nyika pavanenge vachitsvaga rubatsiro rwekurapa kunze kwenyika. Saka, takagadzira nzira dzekutaurirana dziri nyore uye dzakasiyana-siyana kuitira kuti mugone kuwana ruzivo rwehutano rwechokwadi uye kutanga maitiro ekurapa.
**Nzira Yekubata Nayo Inodiwa:**
* Nhare yekubatsira varwere vepasi rose: 400-880-3716
**Nzira dzakasiyana-siyana dzekutaurirana:**
* Kubvunzana paWeChat: Wedzerai ID “17801183037″ kuti muwane mazano anoenderana nemeseji uye mhinduro dzinokurumidza.
* Kubvunzana Neemail:
* General Inquiry: 100085_010@163.com
* International Medical Exclusive: myimmnet@163.com
**Maitiro Evarwere Vepasi Pose:**
1. Bata Murongi wedu weVarwere Wepasi Pose uchishandisa chero nzira dziri pamusoro apa.
2. Tumira zvinyorwa zvekurapa kuti zviongororwe pakutanga (kusanganisira mishumo yezvirwere, mhedzisiro yekuongororwa kwemajini, nezvimwewo).
3. Ronga kubvunzana nenyanzvi yezvirwere zvegomarara iri kure nevhidhiyo.
4. Kana kurapwa muChina kuchidikanwa, tichabatsira nekugadzirisa mavhiza ekurapa, kuronga pekugara, nezvimwe zvinhu.
5. Nakidzwa nekurapwa kamwe chete paunosvika muBeijing, kubva pakutorwa nendege kusvika parwendo rwese rwekurapwa.
**Chiyeuchidzo Chinokosha: Kuongororwa Kwemajini Pamberi Pekurapwa Kwakakosha**
Semushonga unotariswa, kushanda kwezurletrectinib kunoenderana zvakanyanya nekuongororwa kwemajini kwakarurama. Tinokurudzira kuti varwere vese vari kufunga nezvekurapa uku vatange vaongororwa majini eNTRK. Dhipatimendi reBeijing South Region Oncology Hospital International rinogona kuronga masevhisi ekuongororwa anozivikanwa pasi rose kana kupa dudziro yepamutemo yemhedzisiro yako yebvunzo iripo.
**Kutarisa Mberi: Nguva Itsva Yekurapwa Kwegomarara Kwakasiyana-siyana**
Kubvumidzwa kwemushonga we zurletrectinib hakusi kungoburitswa kwemushonga mutsva chete; humbowo hwakasimba hwehunyanzvi hweChina mukurapa kenza nenzira chaiyo. Dhipatimendi reBeijing South Region Oncology Hospital International richaramba richitevera kufambira mberi kwepasi rose mukurapa kenza, kubatanidza zviwanikwa zvekurapa zvemhando yepamusoro kubva kuzvipatara zvemuno nezvekunze kwenyika, uye kupa masevhisi ekuongorora kenza uye ekurapa emhando yepamusoro, anotarisana nemurwere kune varwere vekunze kwenyika.
**Fonera izvozvi kuti ubvunze kana iwe kana mudiwa wako muri mumiriri wekurapa uku kutsva!**
Nhare yeBeijing South Region Oncology Hospital International Department International Patient Hotline: 400-880-3716
Nhamba yeWeChat: 17801183037
Email: 100085_010@163.com; myimmnet@163.com
**Cherechedza:** Ruzivo rwezvekurapa rwuri muchinyorwa chino rwakavakirwa padata rekuyedza kwekiriniki riripo pachena. Zvirongwa zvekurapa zvakananga zvinofanirwa kuumbwa navanachiremba vane hunyanzvi zvichienderana nemamiriro emurwere mumwe nemumwe. Zvinokurudzirwa kuti varwere vese vabvunze nyanzvi dzehutano dzakanyatsokodzera vasati vafunga nezvekurapa kupi zvako.
Nguva yekutumira: Zvita-31-2025