Musi wa21 Kubvumbi, 2026, Center for Drug Evaluation (CDE) yeNational Medical Products Administration yakazivisa kuti HS-20093 yekubaiwa jekiseni (risvutatug rezetecan) yakasarudzwa semushonga weBreakthrough Therapy wekurapa varwere vane kenza yeprostate inoramba kurapwa ne castration avo vakambogamuchira mushonga mutsva wehomoni uye chemotherapy. Mashoko aya anounza tariro itsva kune varwere vekenza yeprostate pasi rese.
HS-20093 (HS-20093 / GSK5764227) iB7-H3-targeting antibody-drug conjugate (ADC) yakagadzirwa yega neHansoh. Pa2026 American Society of Clinical Oncology Genitourinary Cancers Symposium (ASCO GU 2026), mhedzisiro kubva muongororo yePase II yakavhurika, ine nzvimbo dzakawanda inonzi ARTEMIS-003 (NCT06001255) yakapihwa zviri pamutemo. Chidzidzo ichi chakaongorora kushanda uye kuchengetedzeka kweHS-20093 muvarwere vane metastatic castration-resistant prostate cancer (mCRPC) avo vakafambira mberi mushure mekurapwa kamwe chete.
Mhedzisiro yacho yaikurudzira:
- **Muvarwere vakamborapwa ne taxanes:** chiyero chekupindura chakasimbiswa (cORR) chaive 38.9%, uye chiyero chekupindura cheprostate-specific antigen (PSA) (≥50% kudzikira) chaive 40.7%.
- **Muvarwere vasina kurapwa ne taxanes kare:** chiyero chekupindura chakasimbiswa (uORR) chaive 41.7%, uye chiyero chekupindura chePSA50 chaive 23.8%.
Ruzivo urwu runoratidza kuti HS-20093 inoratidza kushanda kwakakosha uye kwakasimba mukurwisa bundu pasinei nechemotherapy yakaitwa kare. Kune varwere vane chirwere chakanyanya kukura avo vakazoramba kurapwa kana kuti vakadzokera shure mushure mekurapwa kwazvino (kurapwa kwehomoni itsva + chemotherapy), izvi hazvina mubvunzo kuti isarudzo itsva uye inobatsira pakurapa.
**Varwere vekune dzimwe nyika vanogona sei kuwana mushonga uyu wepamusoro?**
Kana iwe kana nhengo yemhuri yako iri kurwara nekenza yeprostate isingapindi mukenza uye isingagutsikane nekurapwa kuripo kana kusashivirira, unogona ikozvino kubvunza neInternational Department yeBeijing South Region Oncology Hospital kuti uone kukodzera kurapwa neHS-20093. Sesangano rakanyatso shanda rinokwanisa kupa mabasa ekurapa epasi rose, International Department yechipatara ichi yakazvipira kupa rubatsiro rwakakwana rwekenza kuvarwere vepasi rose, kusanganisira kuwana miedzo yekiriniki itsva uye mishonga inobudirira.
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- **Nhamba yefoni:** 400-880-3716
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- **Email:**
① 100085_010@163.com
② myimmnet@163.com
**Zvinyorwa Zvakakosha:**
- Varwere vekune dzimwe nyika vasati vashanyira, vanofanira kugadzirira shanduro dzeChirungu/ChiChinese dzezvinyorwa zvekurapa zvekare (kusanganisira mishumo yezvirwere, kuongororwa kwemifananidzo, uye zvinyorwa zvechemotherapy yekare uye kurapwa kwemahormone) kuti zviite kuti kuongororwa kwachiremba kuve nyore.
- Dhipatimendi redu repasi rose rinogona kubatsira netsamba dzekukoka mavhiza ekurapa, nguva dzekugadzwa, uye mabasa ekushandura. Kana muine mibvunzo chaiyo, ndapota taurai nesu kuburikidza nenzira dziri pamusoro apa.
Nguva yekutumira: Kubvumbi-28-2026