Musi wa31 Chikunguru, 2025, ImmuneOnco Biopharmaceuticals yakazivisa ruzivo rwekutanga rwekuchengetedza uye kushanda zvakanaka kubva muongororo yePhase 2 yakavhurika, ine nzvimbo dzakawanda dzekudzidza kweIMM2510 pamwe chete nechemotherapy yevarwere vari pamberi pemushonga vane kenza yemapapu isiri diki (NSCLC) yakaitwa kuChina.
Kubva musi wa1 Chikunguru, 2025, varwere makumi matatu nematatu vakapihwa mushonga we10 mg/kg, varwere makumi maviri nerimwe vakaongororwa bundu kamwe chete (kuongororwa kushanda kwaro). Mhinduro dzisina kukwana dzakaonekwa mu62% yevarwere vakaongororwa kushanda kwaro, dzinosanganisira mhinduro dzisina kukwana mu80% (8/10) yevarwere vane squamous NSCLC uye 46% (5/11) yevarwere vane non-squamous NSCLC. Ruzhinji rwevarwere vakaongororwa kushanda kwaro rwaive nebvundu rimwe chete pakuchekwa kwedata. ImmuneOnco inotarisira kupa data rekuchengetedza uye kushanda kwaro muIMM2510 chemotherapy combination trial muNSCLC yepamberi pamusangano wezvekurapa wemangwana.
Ruzivo rwekuchengetedza rweIMM2510 runotsigira kukura kwekiriniki, pasina chepfu inoganhurira dose yakaonekwa muvarwere makumi matatu nevatatu vanoongororwa kuchengetedzeka. Muvarwere ava, hapana zviitiko zvakaipa zvine chekuita nekurapwa (TRAE) zvakakonzera kudzikiswa kwedose kana kufa, uye TRAE imwe chete yakakonzera kurega kushandisa mushonga. MaTRAE akajairika eGiredhi 3+ aive eropa, ane zvimwe zvisingawanzoitiki zvekiriniki. Zviitiko zvakaipa zvinowanzobatanidzwa nekudziviswa kweVEGF (semuenzaniso, BP, proteinuria, hemoptysis) uye zviitiko zvakaipa zvine chekuita neimmune zvaive zvisingawanzoitiki uye kazhinji zvaive zvegiredhi rakaderera, uye maitiro ane chekuita neinfusion aive ese ari egiredhi rakaderera.
Parizvino, kuchine miedzo yakawanda yekiriniki yehunyanzvi hutsva hwekurwisa gomarara muChina huri kutsvaga varwere. Kana muchida kubvunzana nezvemishonga mitsva netekinoroji, munogona kubata Dhipatimendi reBeijing South Region Oncology Hospital International.
Nhamba yefoni: 4008803716
Nhamba yeWeChat: 17801183037
Email：myimmnet@163.com
Nguva yekutumira: Nyamavhuvhu-05-2025