Chinyorwa chazvino cheWorld Health Organization's Classification of Soft Tissue and Bone Tumors, chakaburitswa muna Kubvumbi 2020, chinopa mutsauko.sarcomamuzvikamu zvitatu: sbundu renyama dzakawanda, bundu remapfupa, uye bundu remapfupa nenyama yakapfava rine masero madiki akatenderera asina kusiyanisa(senge EWSR1-non-ETS fusion round cell sarcoma).
"Kenza Yakakanganwika"
Sarcoma rudzi rusingawanzoitiki rwechirwerekenza muvanhu vakuru, tichitarisa nezve1%yegomarara rese revanhu vakuru, rinowanzonzi "Kenza Yakakanganwika." Zvisinei, iri pakati nepakatiinowanikwa muvana, tichitarisa zvinenge15% kusvika 20%yegomarara revana vese. Rinogona kuitika chero kunhengo ipi zvayo yemuviri, kazhinji mumaoko kana makumbo(60%), ichiteverwa nehunde kana dumbu(30%), uye pakupedzisiramusoro kana mutsipa(10%).
Mumakore achangopfuura, kuwanda kwemabundu emapfupa nenyama yakapfava kwave kuwedzera zvishoma nezvishoma. Mabundu emapfupa ekutanga anonyanya kuipa muvechidiki nevanhu vane makore epakati uye anosanganisira osteosarcoma, Ewing sarcoma, chondrosarcoma, malignant fibrous histiocytoma, uye chordoma, pakati pemamwe. Mabundu emapfupa akapfava anowanzoonekwa anosanganisira synovial sarcoma, fibrosarcoma, liposarcoma, uye rhabdomyosarcoma. Kupararira kwemapfupa kunowanzoonekwa muvanhu vane makore epakati nepakati nevakwegura, uye mabundu epakutanga anowanzoonekwa ari kenza yemapapu, kenza yemazamu, kenza yeitsvo, kenza yeprostate, uye kenza yethyroid, pakati pemamwe.
Kuonekwa Kwekutanga, Kurapwa Kwekutanga - Kuvhenekera "Mamota" Akavanzika
Nekuda kwehuwandu hwakawanda hwekudzokororwa kwesarcomas, mabundu mazhinji haana kunyatsojeka kuongororwa kwechirwere asati avhiyiwa uye haana kuongororwa kwakadzama kwemifananidzo. Izvi zvinowanzoita kuti panguva yekuvhiyiwa zvionekwe kuti bundu harisi nyore sezvinofungidzirwa usati wavhiyiwa, zvichikonzera kubviswa kwechirwere chisina kukwana. Kudzokororwa kwechirwere mushure mekuvhiyiwa kana metastasis kunogona kuitika, zvichiita kuti varwere vasawane mukana wekurapwa wakakodzera. Nokudaro,Kuonekwa kwekutanga, kuongororwa kwakarurama, uye kurapwa nenguva zvine simba guru pakufanotaura kwevarwere. Nhasi, tinoda kukuzivisai nyanzvi inoremekedzwa ine ruzivo rwemakore anoda kusvika makumi maviri.mukuongorora kwakajairika uye kurapwa kwakagadzirirwa munhu wega wega kwesarcoma yenyama yakapfava, uye inorumbidzwa zvikuru neindasitiri nevarwere -ChirembaLiu Jiayongkubva kuDhipatimendi reMapfupa neNyama Yakapfava paPeking University Cancer Hospital.
Kuburitsa Nyanzvi ine Ruzivo Rwakadzama rweMarwadzo eMapfupa neNyama – Dr..Liu Jiayong
Chiremba weMishonga, Chiremba Mukuru, Purofesa Akabatana. Akadzidza paAnderson Cancer Center muUnited States.
Hunyanzvi:Kurapa kwakakwana kwe soft tissue sarcomas (kuvhiyiwa nekugadziriswazve; chemotherapy, kurapwa kwakanangana, uye immunotherapy); kurapwa kwekuvhiyiwa kwe melanomas.
Nemakore anoda kusvika makumi maviri eruzivo rwekurapa, Doctor Liu Jiayong vakaunganidza ruzivo rwakakura rwekurapa nekurapa kwekuvhiya mukuongororwa kwakajairika uye zvirongwa zvekurapa zvakagadzirirwa munhu wegakune common soft tissue sarcomas dzakadai se undifferentiated pleomorphic sarcoma, liposarcoma, leiomyosarcoma, synovial sarcoma, adenocystic carcinoma-like sarcoma, epithelioid sarcoma, fibrosarcoma, angiosarcoma, uye infiltrative fibromatosis. Anonyanya kurwara.vane hunyanzvi pakubata mitsipa yeropa netsinga panguva yekuvhiyiwa kwesarcoma yemakumbo, pamwe nekugadzirisa nekugadzirazve zvikanganiso zvenyama yakapfava paganda.Chiremba Liu anoteerera murwere wega wega nemwoyo murefu, anobvunza nokungwarira nezvenhoroondo yezvekurapa kwavo, uye anotora zvinyorwa zvekurapa zvakanyatsonaka. Anonyanya kutarisisa shanduko dziri muhutano hwemurwere panguva dzakasiyana, dzakadai seasati avhiyiwa uye avhiyiwa, panguva yekurapwa, kutevera, uye kufambira mberi kwechirwere, achiita zvisarudzo zvakarurama uye kugadzirisa zvirongwa zvekurapa nenguva.
Chiremba Liu Jiayong parizvino anoshanda senhengo yeSoft Tissue Sarcoma and Melanoma Group yeChinese Anti-Cancer Association, pamwe nenhengo yeBone Tumor Group yeBeijing Society of Orthopedics yeChinese Medical Association.Muna 2010, ndiye akatanga kuChina kushandura nekuburitsa "NCCN Clinical Practice Guidelines in Soft Tissue Sarcoma," achikurudzira kurapwa kwakajairika kwemasarcoma enyama yakapfava.Anoramba achiedza kufambira mberi mukutsvagisa kwekiriniki nesainzi, kunyangwe aine varwere vakawanda. Akazvipira uye ane mutoro kune murwere wese waanorapa, uye panguva yedenda, akagadzirisa matambudziko anosangana nevarwere vari kutsvaga rubatsiro rwekurapa nekupindura nekukurumidza kubvunzurudzo dzevarwere, kuongorora mhedzisiro yekutevera, uye kupa mazano akakodzera ekurapwa kuburikidza nemapuratifomu ekukurukurirana epamhepo akadai seGood Doctor's Patient Group.
Nyaya Ichangoburwa
VaZhang, murwere ane makore makumi matatu nemashanu ekuberekwa, vakaerekana varasikirwa nekuona pakutanga kwa2019. Mushure mezvo, vakavhiyiwa ziso rekuruboshwe nekuda kwekuwedzera kwekumanikidzwa kwemukati meziso. Pathology mushure mekuvhiyiwa yakaratidza pseudobumor inoputika. Muzhizha regore rimwe chete, maronda akawanda emapapu akawanikwa panguva yekuongororwa kwekutevera, asi hapana masero egomarara akaonekwa kuburikidza nekuongorora netsono. Kuongororwa kwakatevera kwakaratidza metastases yakawanda yemapfupa nemapapu. Kubvunzana muzvipatara zvemuno nezvepamusoro kwakamuwana aine bundu remyofibroblastic rinoputika. Muna Nyamavhuvhu 2022, akarapwa chemotherapy yakawanda, iyo yakaderedza marwadzo ake zvakanyanya asi haina kuratidza kuvandudzika kuri pachena mumaronda paakaongororwazve. Mamiriro ake emuviri akadererawo. Pasinei neizvi, mhuri yake haina kumborega tariro. Mushure mekutsvaga pfungwa dzakawanda, dzakauya kuna Doctor Liu Jiayong muna Mbudzi 2022. Mushure mekunyatsoongorora nhoroondo yekurapa yemurwere, zvinyorwa zvese zvekurapa, bvunzo dzezvirwere, uye data remifananidzo,ChirembaLiu akakurudzira mushonga wekurapa chemotherapy une methotrexate ine dose shoma uye Changchun Ruibin.Kurapwa kwemishonga iyi hakudhuri zvakanyanya uye hakuna migumisiro yakawanda. Mushure memazuva makumi matatu nemashanu ekurapwa, CT scan yakatevera yakaratidza kuti bundu riri mumapapu ekurudyi rakanga ranyangarika, zvichiratidza kudzora bundu zvakanaka.Ongororo yekutevera yakaitwa munguva pfupi yapfuura paBeijing South Region Oncology Hospital yakaratidza kuti mapapu ake akamira zvakanaka, uye Doctor Liu akakurudzira kuti agare achiongororwa. Murwere nemhuri yake vava nechivimbo chikuru mukurapwa kwacho, vazere netariro. Vanonzwa kuti vakaona chiedza murwendo rwekurapwa uye vanoratidza kutenda kwavo nemwoyo wese nekupa bhana resiriki rekuonga.
Nguva yekutumira: Nyamavhuvhu-25-2023